Key role of the GITR/GITRLigand pathway in the development of murine autoimmune diabetes: a potential therapeutic target.

Key role of the GITR/GITRLigand pathway in the development of murine autoimmune diabetes: a potential therapeutic target.

The cross-talk between pathogenic T lymphocytes and regulatory T cells (Tregs) plays a major role in the progression of autoimmune diseases. Our objective is to identify molecules and/or pathways involved in this interaction and representing potential targets for innovative therapies. Glucocorticoid...

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Bibliographic Details
Main Authors: Sylvaine You, Lynn Poulton, Steve Cobbold, Chih-Pin Liu, Michael Rosenzweig, Douglas Ringler, Wen-Hui Lee, Berta Segovia, Jean-François Bach, Herman Waldmann, Lucienne Chatenoud
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2775640?pdf=render

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http://europepmc.org/articles/PMC2775640?pdf=render

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