Dose–response correlation for CAR-T cells: a systematic review of clinical studies

The potential of chimeric antigen receptor (CAR) T cells to successfully treat hematological cancers is widely recognized. Multiple CAR-T cell therapies are currently under clinical development, with most in early stage, during which dose selection is a key goal. The objective of this review is to a...

Full description

Bibliographic Details
Main Authors: Christopher Heery, Matthew J Frigault, Bijal Shah, Anand Rotte, Ayub Ansari, Brad Gliner
Format: Article
Language:English
Published: BMJ Publishing Group 2022-12-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/10/12/e005678.full