Harnessing conserved signaling and metabolic pathways to enhance the maturation of functional engineered tissues
Abstract The development of induced-pluripotent stem cell (iPSC)-derived cell types offers promise for basic science, drug testing, disease modeling, personalized medicine, and translatable cell therapies across many tissue types. However, in practice many iPSC-derived cells have presented as immatu...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-09-01
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Series: | npj Regenerative Medicine |
Online Access: | https://doi.org/10.1038/s41536-022-00246-3 |