Polygenic risk score model for renal cell carcinoma in the Korean population and relationship with lifestyle-associated factors

Polygenic risk score model for renal cell carcinoma in the Korean population and relationship with lifestyle-associated factors

Abstract Background The polygenic risk score (PRS) is used to predict the risk of developing common complex diseases or cancers using genetic markers. Although PRS is used in clinical practice to predict breast cancer risk, it is more accurate for Europeans than for non-Europeans because of the samp...

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Bibliographic Details
Main Authors: Joo Young Hong, Jang Hee Han, Seung Hwan Jeong, Cheol Kwak, Hyeon Hoe Kim, Chang Wook Jeong
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Genomics
Subjects:
Polygenic risk score
Genome-wide association study
Renal cell carcinoma
Korean population
Non-coding variant
Epigenetics
Online Access:https://doi.org/10.1186/s12864-024-09974-w

Internet

https://doi.org/10.1186/s12864-024-09974-w

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