Computer simulation of neutral drift among limbal epithelial stem cells of mosaic mice

The use of mice that are mosaic for reporter gene expression underlies many lineage-tracing studies in stem cell biology. For example, using mosaic LacZ reporter mice, it was shown that limbal epithelial stem cells (LESCs) around the periphery of the cornea maintain radial sectors of the corneal epi...

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Bibliographic Details
Main Authors: John D. West, Richard L. Mort, Robert E. Hill, Steven D. Morley, J. Martin Collinson
Format: Article
Language:English
Published: Elsevier 2018-07-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506118301211