Thiazolidinedione Derivatives: In Silico, In Vitro, In Vivo, Antioxidant and Anti-Diabetic Evaluation

Thiazolidinedione Derivatives: In Silico, In Vitro, In Vivo, Antioxidant and Anti-Diabetic Evaluation

This work aimed to synthesize a new antihyperglycemic thiazolidinedione based on the spectral data. The DFT\B3LYP\6-311G** level of theory was used to investigate the frontier molecular orbitals (FMOs), chemical reactivity and map the molecular electrostatic potentials (MEPs) to explain how the synt...

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Bibliographic Details
Main Authors: Manal Y. Sameeh, Manal M. Khowdiary, Hisham S. Nassar, Mahmoud M. Abdelall, Hamada H. Amer, Abdelaaty Hamed, Ahmed A. Elhenawy
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Molecules
Subjects:
thiazolidinediones
anti-diabetic
antioxidant
molecular docking
Online Access:https://www.mdpi.com/1420-3049/27/3/830

Internet

https://www.mdpi.com/1420-3049/27/3/830

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