Targeted Antivascular Therapy with the Apolipoprotein(a) Kringle V, rhLK8, Inhibits the Growth and Metastasis of Human Prostate Cancer in an Orthotopic Nude Mouse Model

Antivascular therapy has emerged as a rational strategy to improve the treatment of androgen-independent prostate cancer owing to the necessity of establishing a vascular network for the growth and progression of the primary and metastatic tumor. We determined whether recombinant human apolipoprotei...

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Bibliographic Details
Main Authors: Ho-Jeong Lee, Hyun-Kyung Yu, John N. Papadopoulos, Seung Wook Kim, Junqin He, Yong-Keun Park, Yeup Yoon, Jang-Seong Kim, Sun Jin Kim
Format: Article
Language:English
Published: Elsevier 2012-04-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558612800704