Low expression of PEBP1P2 promotes metastasis of clear cell renal cell carcinoma by post-transcriptional regulation of PEBP1 and KLF13 mRNA

Low expression of PEBP1P2 promotes metastasis of clear cell renal cell carcinoma by post-transcriptional regulation of PEBP1 and KLF13 mRNA

Abstract Background Pseudogenes play an essential role in tumor occurrence and progression. However, the functions and mechanisms of pseudogenes in clear cell renal cell carcinoma (ccRCC) remain largely elusive. Methods We quantified PEBP1P2 expression in ccRCC tissues and cells using fluorescence i...

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Bibliographic Details
Main Authors: Lei Yang, Haoli Yin, Yi Chen, Chun Pan, Hexing Hang, Yanwen Lu, Wenliang Ma, Xin Li, Weidong Gan, Hongqian Guo, Dongmei Li
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Experimental Hematology & Oncology
Subjects:
PEBP1P2
m5C modification
Clear cell renal cell carcinoma
PEBP1
KLF13
Online Access:https://doi.org/10.1186/s40164-022-00346-2

Internet

https://doi.org/10.1186/s40164-022-00346-2

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