Cell type characterization of spatiotemporal gene co-expression modules in Down syndrome brain

Summary: Down syndrome (DS) is the most common genetic cause of intellectual disability and increases the risk of other brain-related dysfunctions, like seizures, early-onset Alzheimer’s disease, and autism. To reveal the molecular profiles of DS-associated brain phenotypes, we performed a meta-data...

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Bibliographic Details
Main Authors: Sihwan Seol, Joonhong Kwon, Hyo Jung Kang
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222021575