Serum Neutralizing and Enhancing Effects on African Swine Fever Virus Infectivity in Adherent Pig PBMC

Serum Neutralizing and Enhancing Effects on African Swine Fever Virus Infectivity in Adherent Pig PBMC

African swine fever virus (ASFV) causes hemorrhagic fever with mortality rates of up to 100% in domestic pigs. Currently, there are no commercial vaccines for the disease. Only some live-attenuated viruses have been able to protect pigs from ASFV infection. The immune mechanisms involved in the prot...

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Bibliographic Details
Main Authors: Jessica A. Canter, Theresa Aponte, Elizabeth Ramirez-Medina, Sarah Pruitt, Douglas P. Gladue, Manuel V. Borca, James J. Zhu
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Viruses
Subjects:
African swine fever virus (ASFV)
hyperimmune serum
virus neutralization
flow cytometry
monocyte-derived macrophage
extracellular virions
Online Access:https://www.mdpi.com/1999-4915/14/6/1249

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https://www.mdpi.com/1999-4915/14/6/1249

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