PEG 400:Trehalose Coating Enhances Curcumin-Loaded PLGA Nanoparticle Internalization in Neuronal Cells

PEG 400:Trehalose Coating Enhances Curcumin-Loaded PLGA Nanoparticle Internalization in Neuronal Cells

This work proposes a combination of polyethylene glycol 400 (PEG) and trehalose as a surface modification approach to enhance PLGA-based nanoparticles as a drug carrier for neurons. PEG improves nanoparticles’ hydrophilicity, and trehalose enhances the nanoparticle’s cellular internalization by indu...

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Bibliographic Details
Main Authors: Isaac H. Caballero-Florán, Hernán Cortés, Fabiola V. Borbolla-Jiménez, Carla D. Florán-Hernández, María L. Del Prado-Audelo, Jonathan J. Magaña, Benjamín Florán, Gerardo Leyva-Gómez
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Pharmaceutics
Subjects:
trehalose
polyethylene glycol
PEG
nanoprecipitation
nanoparticles
PLGA
Online Access:https://www.mdpi.com/1999-4923/15/6/1594

Internet

https://www.mdpi.com/1999-4923/15/6/1594

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