Methoxy and methylthio-substituted trans-stilbene derivatives as CYP1B1 inhibitors – QSAR study with detailed interpretation of molecular descriptors
A quantitative structure–activity relationship (QSAR) model was built using multiple linear regression (MLR) to predict the ability of series methyl and/or methylthio trans-stilbene derivatives to inhibit CYP1B1. Twenty-four compounds with their activity expressed as the negative log of the IC50 val...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2022-11-01
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| Series: | Arabian Journal of Chemistry |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1878535222005202 |