Across the stages: a multiscale extension of the generalized stochastic microdosimetric model (MS-GSM2) to include the ultra-high dose rate

Across the stages: a multiscale extension of the generalized stochastic microdosimetric model (MS-GSM2) to include the ultra-high dose rate

Ultra-high dose rate (UHDR) irradiations with different types of radiation have shown a larger sparing of normal tissue and unchanged tumor control with respect to conventional delivery. In recent years, there has been an accumulation of experimental evidence related to the so-called FLASH effect. H...

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Bibliographic Details
Main Authors: Marco Battestini, Marta Missiaggia, Andrea Attili, Francesco Tommasino, Chiara La Tessa, Francesco G. Cordoni, Emanuele Scifoni
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Physics
Subjects:
FLASH effect
ultra-high dose rate biological mechanism
radiation chemistry
multi-stage radiobiological model
multiscale generalized stochastic microdosimetric model
Online Access:https://www.frontiersin.org/articles/10.3389/fphy.2023.1274064/full

Internet

https://www.frontiersin.org/articles/10.3389/fphy.2023.1274064/full

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