Innovative Animal Model of DSS-Induced Ulcerative Colitis in Pseudo Germ-Free Mice

Innovative Animal Model of DSS-Induced Ulcerative Colitis in Pseudo Germ-Free Mice

The aim of this study was to investigate the use of a standardized animal model subjected to antibiotic treatment, and the effects of this treatment on the course of dextran sodium sulphate (DSS)-induced colitis in mice. By decontamination with selective antibiotics and observation of pathogenesis o...

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Bibliographic Details
Main Authors: Sona Gancarcikova, Stanislav Lauko, Gabriela Hrckova, Zuzana Andrejcakova, Vanda Hajduckova, Marian Madar, Livia Kolesar Fecskeova, Dagmar Mudronova, Kristina Mravcova, Gabriela Strkolcova, Radomira Nemcova, Jana Kacirova, Andrea Staskova, Stefan Vilcek, Alojz Bomba
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cells
Subjects:
pseudo germ-free model
antibiotics
DSS-induced colitis
gut microbiota
histopathology
Online Access:https://www.mdpi.com/2073-4409/9/12/2571

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https://www.mdpi.com/2073-4409/9/12/2571

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