Zfp57 mutant ES cell lines directly derived from blastocysts

Zfp57 is a master regulator of genomic imprinting in mouse embryos. To further test its functions, we have derived multiple Zfp57 mutant ES clones directly from mouse blastocysts. Indeed, we found DNA methylation imprint was lost at most examined imprinting control regions in these Zfp57 mutant ES c...

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Dades bibliogràfiques
Autors principals: Ho-Tak Lau, Lizhi Liu, Xiajun Li
Format: Article
Idioma:English
Publicat: Elsevier 2016-03-01
Col·lecció:Stem Cell Research
Accés en línia:http://www.sciencedirect.com/science/article/pii/S1873506116000027