Zfp57 mutant ES cell lines directly derived from blastocysts

Zfp57 is a master regulator of genomic imprinting in mouse embryos. To further test its functions, we have derived multiple Zfp57 mutant ES clones directly from mouse blastocysts. Indeed, we found DNA methylation imprint was lost at most examined imprinting control regions in these Zfp57 mutant ES c...

Полное описание

Библиографические подробности
Главные авторы: Ho-Tak Lau, Lizhi Liu, Xiajun Li
Формат: Статья
Язык:English
Опубликовано: Elsevier 2016-03-01
Серии:Stem Cell Research
Online-ссылка:http://www.sciencedirect.com/science/article/pii/S1873506116000027