Zfp57 mutant ES cell lines directly derived from blastocysts

Zfp57 is a master regulator of genomic imprinting in mouse embryos. To further test its functions, we have derived multiple Zfp57 mutant ES clones directly from mouse blastocysts. Indeed, we found DNA methylation imprint was lost at most examined imprinting control regions in these Zfp57 mutant ES c...

全面介紹

書目詳細資料
Main Authors: Ho-Tak Lau, Lizhi Liu, Xiajun Li
格式: Article
語言:English
出版: Elsevier 2016-03-01
叢編:Stem Cell Research
在線閱讀:http://www.sciencedirect.com/science/article/pii/S1873506116000027