Neuropathology of phenylketonuria (PKU)
Untreated phenylketonuria (PKU) causes cognitive, neuropsychological and motor skills impairment as well as microcephaly and demyelization. Persistent hyperphenylalaninemia produces toxicity on neurons and glial cells, alters cortical development, growth and dendritic density High levels of phenylal...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | Spanish |
| Published: |
Instituto Nacional de Pediatría
2014-07-01
|
| Series: | Acta Pediátrica de México |
| Subjects: | |
| Online Access: | http://ojs.actapediatrica.org.mx/index.php/APM/article/view/599 |