The Protective Effect of Bergamot Polyphenolic Fraction (BPF) on Chemotherapy-Induced Neuropathic Pain

The Protective Effect of Bergamot Polyphenolic Fraction (BPF) on Chemotherapy-Induced Neuropathic Pain

Paclitaxel is a chemotherapeutic drug used for cancer treatment. Chemotherapy-induced peripheral neuropathy (CIPN) is a common major dose-limiting side effect of many chemotherapeutic agents, including paclitaxel. CIPN is accompanied by mechanical and thermal hypersensitivity that resolves within we...

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Bibliographic Details
Main Authors: Sara Ilari, Filomena Lauro, Luigino Antonio Giancotti, Valentina Malafoglia, Concetta Dagostino, Micaela Gliozzi, Antonia Condemi, Jessica Maiuolo, Francesca Oppedisano, Ernesto Palma, Carlo Tomino, Daniela Salvemini, Vincenzo Mollace, Carolina Muscoli
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Pharmaceuticals
Subjects:
oxidative stress
chemotherapy-induced peripheral neuropathy (CIPN)
natural antioxidants
bergamot polyphenol fraction (BPF)
chronic pain
Online Access:https://www.mdpi.com/1424-8247/14/10/975

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https://www.mdpi.com/1424-8247/14/10/975

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