Celecoxib-Loaded Solid Lipid Nanoparticles for Colon Delivery: Formulation Optimization and In Vitro Assessment of Anti-Cancer Activity

Celecoxib-Loaded Solid Lipid Nanoparticles for Colon Delivery: Formulation Optimization and In Vitro Assessment of Anti-Cancer Activity

This work aimed to optimize a celecoxib (CXB)-loaded solid lipid nanoparticles (SLN) colon delivery system for the enhancement of anticancer activity. An ultrasonic melt-emulsification method was employed in this work for the preparation of SLN. The physical attributes were characterized for their p...

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Bibliographic Details
Main Authors: Hamdan N. Alajami, Ehab A. Fouad, Abdelkader E. Ashour, Ashok Kumar, Alaa Eldeen B. Yassin
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Pharmaceutics
Subjects:
solid lipid nanoparticles
ultrasonic melt-emulsification
celecoxib
HT29
MTT
zeta-potential
Online Access:https://www.mdpi.com/1999-4923/14/1/131

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https://www.mdpi.com/1999-4923/14/1/131

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