Curcumin and derivatives function through protein phosphatase 2A and presenilin orthologues in Dictyostelium discoideum

Curcumin and derivatives function through protein phosphatase 2A and presenilin orthologues in Dictyostelium discoideum

Natural compounds often have complex molecular structures and unknown molecular targets. These characteristics make them difficult to analyse using a classical pharmacological approach. Curcumin, the main curcuminoid of turmeric, is a complex molecule possessing wide-ranging biological activities, c...

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Bibliographic Details
Main Authors: Marco Cocorocchio, Amy J. Baldwin, Balint Stewart, Lou Kim, Adrian J. Harwood, Christopher R. L. Thompson, Paul L. R. Andrews, Robin S. B. Williams
Format: Article
Language:English
Published: The Company of Biologists 2018-01-01
Series:Disease Models & Mechanisms
Subjects:
Dictyostelium discoideum
Curcumin
Presenilin
PP2A
Cancer
Alzheimer's disease
Online Access:http://dmm.biologists.org/content/11/1/dmm032375

Internet

http://dmm.biologists.org/content/11/1/dmm032375

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