Cheminformatics Identification of Phenolics as Modulators of Penicillin-Binding Protein 2a of <i>Staphylococcus aureus</i>: A Structure–Activity-Relationship-Based Study

The acquisition of penicillin-binding protein (PBP) 2a in resistant strains of <i>Staphylococcus aureus</i> allows for the continuous production of cell walls even after the inactivation of intrinsic PBPs. Thus, the discovery of novel therapeutics with enhanced modulatory activity on PBP...

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Bibliographic Details
Main Authors: Jamiu Olaseni Aribisala, Saheed Sabiu
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/14/9/1818