Cheminformatics Identification of Phenolics as Modulators of Penicillin-Binding Protein 2a of <i>Staphylococcus aureus</i>: A Structure–Activity-Relationship-Based Study
The acquisition of penicillin-binding protein (PBP) 2a in resistant strains of <i>Staphylococcus aureus</i> allows for the continuous production of cell walls even after the inactivation of intrinsic PBPs. Thus, the discovery of novel therapeutics with enhanced modulatory activity on PBP...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-08-01
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Series: | Pharmaceutics |
Subjects: | |
Online Access: | https://www.mdpi.com/1999-4923/14/9/1818 |