Dasabuvir Inhibits Human Norovirus Infection in Human Intestinal Enteroids

Dasabuvir Inhibits Human Norovirus Infection in Human Intestinal Enteroids

ABSTRACT Human noroviruses (HuNoVs) are acute viral gastroenteritis pathogens that affect all age groups, yet no approved vaccines and drugs to treat HuNoV infection are available. In this study, we screened an antiviral compound library to identify compound(s) showing anti-HuNoV activity using a hu...

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Bibliographic Details
Main Authors: Tsuyoshi Hayashi, Kosuke Murakami, Junki Hirano, Yoshiki Fujii, Yoko Yamaoka, Hirofumi Ohashi, Koichi Watashi, Mary K. Estes, Masamichi Muramatsu
Format: Article
Language:English
Published: American Society for Microbiology 2021-12-01
Series:mSphere
Subjects:
acute gastroenteritis
antiviral drug
compound screen
dasabuvir
intestinal enteroids
norovirus
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00623-21

Internet

https://journals.asm.org/doi/10.1128/mSphere.00623-21

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