The role of elastin on the mechanical properties of the anterior leaflet in porcine tricuspid valves.

Elastin is present in the extracellular matrix (ECM) of connective tissues, and its mechanical properties are well documented. In Marfan syndrome, however, the inability to properly code for the protein fibrillin-1 prematurely leads to the degradation and loss of elastin fiber integrity in the ECM....

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Bibliographic Details
Main Authors: Samuel D Salinas, Yasmeen M Farra, Keyvan Amini Khoiy, James Houston, Chung-Hao Lee, Chiara Bellini, Rouzbeh Amini
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0267131