Aspects of VLA-4 and LFA-1 regulation that may contribute to rolling and firm adhesion

Very Late Antigen -4 (CD49d/CD29, alpha4 beta1) and Lymphocyte Function-associated Antigen-1 (CD11a/CD18, alphaL beta2) integrins are representatives of a large family of adhesion receptors widely expressed on immune cells. They participate in cell recruitment to sites of inflammation, as well as mu...

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Bibliographic Details
Main Authors: Alexandre eChigaev, Larry A Sklar
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-08-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00242/full