Obesity/Type II diabetes alters macrophage polarization resulting in a fibrotic tendon healing response.

Type II Diabetes (T2DM) dramatically impairs the tendon healing response, resulting in decreased collagen organization and mechanics relative to non-diabetic tendons. Despite this burden, there remains a paucity of information regarding the mechanisms that govern impaired healing of diabetic tendons...

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Bibliographic Details
Main Authors: Jessica E Ackerman, Michael B Geary, Caitlin A Orner, Fatima Bawany, Alayna E Loiselle
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5501654?pdf=render