Long-term protection against HBV chronic carriage of Gambian adolescents vaccinated in infancy and immune response in HBV booster trial in adolescence.

BACKGROUND:Chronic infection with hepatitis B virus (HBV) arising in childhood is associated with hepatocellular carcinoma in adult life. Between 1986 and 1990, approximately 120,000 Gambian newborns were enrolled in a randomised controlled trial to assess the effectiveness of infant HBV vaccination...

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Main Authors: Marianne A B van der Sande, Pauline A Waight, Maimuna Mendy, Syed Zaman, Steve Kaye, Omar Sam, Abi Kahn, David Jeffries, Aveika A Akum, Andrew J Hall, Ebrima Bah, Samuel J McConkey, Pierre Hainaut, Hilton C Whittle
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1940311?pdf=render