Circulating levels of AGEs and soluble RAGE isoforms are associated with all-cause mortality and development of cardiovascular complications in type 2 diabetes: a retrospective cohort study

Abstract Background Advanced glycation end-products (AGEs) and their interaction with the receptor for advanced glycation end-products (RAGE) play a pivotal role in the development and progression of type 2 diabetes. In this retrospective cohort study, we explored the association of circulating leve...

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Bibliographic Details
Main Authors: Jacopo Sabbatinelli, Stefania Castiglione, Federica Macrì, Angelica Giuliani, Deborah Ramini, Maria Cristina Vinci, Elena Tortato, Anna Rita Bonfigli, Fabiola Olivieri, Angela Raucci
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Cardiovascular Diabetology
Subjects:
Online Access:https://doi.org/10.1186/s12933-022-01535-3