Chronic intermittent hypoxia increases airway hyperresponsiveness during house dust mites exposures in rats

Abstract Introduction Accumulating clinical evidence links Obstructive Sleep Apnea (OSA) with worse outcomes of asthma, but impact on airway function remains sparsely studied. We tested effects of Chronic Intermittent Hypoxia (CIH) – a hallmark of OSA – on airway hyperresponsiveness (AHR), in a rat...

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Bibliographic Details
Main Authors: Mihaela Teodorescu, Ruolin Song, Jacqueline A. Brinkman, Ronald L. Sorkness
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Respiratory Research
Subjects:
Online Access:https://doi.org/10.1186/s12931-023-02493-4