Production of recombinant DNA fragmentation factor 40 in fusion to an antimicrobial peptide from spider venom and evaluation of its cytotoxic effects

Background and purpose: DNA fragmentation factor 40 (DFF40) as an apoptotic molecule can represent a novel approach to cancer treatment. Lycosin-I (LYC-I), a peptide derived from spider venom, was considered for the targeted delivery of DFF40 to cancer cells. This study attempted to produce soluble...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Zahra Shafiee-Ardestani, Fatemeh Shafiee
Формат: Өгүүллэг
Хэл сонгох:English
Хэвлэсэн: Wolters Kluwer Medknow Publications 2024-01-01
Цуврал:Research in Pharmaceutical Sciences
Нөхцлүүд:
Онлайн хандалт:http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2024;volume=19;issue=1;spage=93;epage=104;aulast=Shafiee-Ardestani