DFFNDDS: prediction of synergistic drug combinations with dual feature fusion networks

DFFNDDS: prediction of synergistic drug combinations with dual feature fusion networks

Abstract Drug combination therapies are promising clinical treatments for curing patients. However, efficiently identifying valid drug combinations remains challenging because the number of available drugs has increased rapidly. In this study, we proposed a deep learning model called the Dual Featur...

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Bibliographic Details
Main Authors: Mengdie Xu, Xinwei Zhao, Jingyu Wang, Wei Feng, Naifeng Wen, Chunyu Wang, Junjie Wang, Yun Liu, Lingling Zhao
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Journal of Cheminformatics
Subjects:
Drug combination
Synergistic effect
Deep learning
Dual-feature fusion
Online Access:https://doi.org/10.1186/s13321-023-00690-3

Internet

https://doi.org/10.1186/s13321-023-00690-3

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