Population Pharmacokinetics of Ropeginterferon Alfa-2b: A Comparison Between Healthy Caucasian and Chinese Subjects

Population Pharmacokinetics of Ropeginterferon Alfa-2b: A Comparison Between Healthy Caucasian and Chinese Subjects

Objective: To develop a population pharmacokinetic (PK) model for ropeginterferon alfa-2b and to compare its PK properties between Caucasian and Chinese populations.Methods: A population PK model was developed based on data from two phase I clinical trials conducted in Caucasian and Chinese individu...

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Bibliographic Details
Main Authors: Min Zhu, Mei-xia Wang, Zi-ran Li, Wei Wang, Xia Su, Zheng Jiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Pharmacology
Subjects:
ropeginterferon alfa-2b
population pharmacokinetics
Chinese
Caucasian
nonlinear mixed effect modeling
ethnic difference
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.673492/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.673492/full

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