A simulation of the random and directed motion of dendritic cells in chemokine fields.

Dendritic cells (DCs) are the most effective professional antigen-presenting cell. They ferry antigen from the extremities to T cells and are essential for the initiation of an adaptive immune response. Despite interest in how DCs respond to chemical stimuli, there have been few attempts to model DC...

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Bibliographic Details
Main Authors: Avery Parr, Nicholas R Anderson, Daniel A Hammer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-10-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1007295