A study of target effect sizes in randomised controlled trials published in the Health Technology Assessment journal

Abstract Background When designing a randomised controlled trial (RCT), an important consideration is the sample size required. This is calculated from several components; one of which is the target difference. This study aims to review the currently reported methods of elicitation of the target dif...

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Bibliographic Details
Main Authors: Joanne C. Rothwell, Steven A. Julious, Cindy L. Cooper
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Trials
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13063-018-2886-y