2-APCAs, the Novel Microtubule Targeting Agents Active against Distinct Cancer Cell Lines

2-APCAs, the Novel Microtubule Targeting Agents Active against Distinct Cancer Cell Lines

Microtubules are known as the most attractive molecular targets for anti-cancer drugs. However, the number of serious limitations of the microtubule targeting agents (MTAs) including poor bioavailability, adverse effects (e.g., systemic and neural toxicity), and acquired resistance after initiation...

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Bibliographic Details
Main Authors: Sergei Boichuk, Aigul Galembikova, Firuza Bikinieva, Pavel Dunaev, Aida Aukhadieva, Kirill Syuzov, Svetlana Zykova, Nazim Igidov, Alexander Ksenofontov, Pavel Bocharov
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Molecules
Subjects:
microtubules
tubulin
cell cycle
mitotic arrest
apoptosis
soft tissue sarcomas (STS)
Online Access:https://www.mdpi.com/1420-3049/26/3/616

Internet

https://www.mdpi.com/1420-3049/26/3/616

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