A hybrid blob-slice model for accurate and efficient detection of fluorescence labeled nuclei in 3D

<p>Abstract</p> <p>Background</p> <p>To exploit the flood of data from advances in high throughput imaging of optically sectioned nuclei, image analysis methods need to correctly detect thousands of nuclei, ideally in real time. Variability in nuclear appearance and und...

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Bibliographic Details
Main Authors: Hadjantonakis Anna-Katerina, Nowotschin Sonja, Du Zhuo, Santella Anthony, Bao Zhirong
Format: Article
Language:English
Published: BMC 2010-11-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/11/580