CARM1 Methylates GAPDH to Regulate Glucose Metabolism and Is Suppressed in Liver Cancer

Summary: Increased aerobic glycolysis is a hallmark of cancer metabolism. How cancer cells coordinate glucose metabolism with extracellular glucose levels remains largely unknown. Here, we report that coactivator-associated arginine methyltransferase 1 (CARM1 or PRMT4) signals glucose availability t...

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Bibliographic Details
Main Authors: Xing-Yu Zhong, Xiu-Ming Yuan, Ying-Ying Xu, Miao Yin, Wei-Wei Yan, Shao-Wu Zou, Li-Ming Wei, Hao-Jie Lu, Yi-Ping Wang, Qun-Ying Lei
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718313706