Rev-erbs and Glia—Implications for Neurodegenerative Diseases

Recently, we described a role for the circadian clock protein and nuclear receptor Rev-erbα in regulating glial activation states in the brain. Deletion of Rev-erbα resulted in microglial as well as astrocytic activation, while a Rev-erbα agonist diminished the severity of lipopolysaccharide (LPS)-i...

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Bibliographic Details
Main Authors: Percy Griffin, Julie M Dimitry, Erik S Musiek
Format: Article
Language:English
Published: SAGE Publishing 2019-06-01
Series:Journal of Experimental Neuroscience
Online Access:https://doi.org/10.1177/1179069519853233