Inducing primary brainstem gliomas in genetically engineered mice using RCAS/TVA retroviruses and Cre/loxP recombination

Inducing primary brainstem gliomas in genetically engineered mice using RCAS/TVA retroviruses and Cre/loxP recombination

Summary: Genetically engineered mice are commonly used to model brainstem gliomas in pre-clinical research. One technique for inducing primary tumors in these genetically engineered mice involves delivering viral vectors containing the code for gene-editing proteins. We present a protocol for genera...

Full description

Bibliographic Details
Main Authors: Loren B. Weidenhammer, Harrison Q. Liu, Lixia Luo, Nerissa T. Williams, Katherine Deland, David G. Kirsch, Zachary J. Reitman
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:STAR Protocols
Subjects:
Cancer
Health Sciences
Microscopy
Model Organisms
Molecular Biology
Neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166723000527

Internet

http://www.sciencedirect.com/science/article/pii/S2666166723000527

Similar Items