Perioperative Dexmedetomidine attenuates brain ischemia reperfusion injury possibly via up-regulation of astrocyte Connexin 43

Abstract Background Astrocyte Connexin 43 (Cx43) is essential for the trophic and protective support of neurons during brain ischemia reperfusion (I/R) injury. It is believed that dexmedetomidine participates in Cx43-mediated effects. However, its mechanisms remained unclear. This study aims to addr...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Xiaoyang Zheng, Xiaoying Cai, Fang Ye, Ying Li, Qin Wang, Zhiyi Zuo, Wenqi Huang, Zhongxing Wang
Μορφή: Άρθρο
Γλώσσα:English
Έκδοση: BMC 2020-12-01
Σειρά:BMC Anesthesiology
Θέματα:
Διαθέσιμο Online:https://doi.org/10.1186/s12871-020-01211-7