Neutralizing Antibodies to Human Cytomegalovirus Recombinant Proteins Reduce Infection in an Ex Vivo Model of Developing Human Placentas

Neutralizing Antibodies to Human Cytomegalovirus Recombinant Proteins Reduce Infection in an Ex Vivo Model of Developing Human Placentas

Human cytomegalovirus (HCMV) is the leading viral cause of congenital disease and permanent birth defects worldwide. Although the development of an effective vaccine is a public health priority, no vaccines are approved. Among the major antigenic targets are glycoproteins in the virion envelope, inc...

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Bibliographic Details
Main Authors: Takako Tabata, Matthew Petitt, Julia Li, Xiaoyuan Chi, Wei Chen, Irina Yurgelonis, Sabine Wellnitz, Simon Bredl, Tiago Vicente, Xinzhen Yang, Philip R. Dormitzer, Lenore Pereira
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Vaccines
Subjects:
cytomegalovirus
vaccine
congenital infection
placenta
Online Access:https://www.mdpi.com/2076-393X/10/7/1074

Internet

https://www.mdpi.com/2076-393X/10/7/1074

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