Ginsenosides Rb1 Attenuates Chronic Social Defeat Stress-Induced Depressive Behavior via Regulation of SIRT1-NLRP3/Nrf2 Pathways

Ginsenosides Rb1 Attenuates Chronic Social Defeat Stress-Induced Depressive Behavior via Regulation of SIRT1-NLRP3/Nrf2 Pathways

Ginsenoside Rb1, a diol-type ginseng saponin, has various positive effects on the central nervous system. This study aimed to evaluate the antidepressant effects of Rb1 on chronic social defeat stress (CSDS) induced behavioral deficits and the exact neural cascades linked with inflammatory processes...

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Bibliographic Details
Main Authors: Ning Jiang, Yiwen Zhang, Caihong Yao, Hong Huang, Qiong Wang, Shuangxue Huang, Qinghu He, Xinmin Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Nutrition
Subjects:
ginsenoside Rb1
depression
CSDS
mice
neuroinflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2022.868833/full

Internet

https://www.frontiersin.org/articles/10.3389/fnut.2022.868833/full

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