The effects of oral administration of Cola nitida on the pharmacokinetic profile of metoclopramide in rabbits
Abstract Background Cola nitida is commonly chewed in many West African cultures to ease hunger pangs and sometimes for their stimulant and euphoriant qualities. Metoclopramide is a known substrate for P-gp, SULT2A1 and CYP2D6 and studies have revealed that caffeine- a major component of Cola nitida...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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BMC
2020-01-01
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| Series: | BMC Pharmacology and Toxicology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40360-019-0379-6 |