Differential expression of notch signaling-related transcripts accompanies Pro-thymocyte proliferation and phenotype transition induced by epidermal growth factor plus insulin in fetal thymus organ cultures

Differential expression of notch signaling-related transcripts accompanies Pro-thymocyte proliferation and phenotype transition induced by epidermal growth factor plus insulin in fetal thymus organ cultures

Thymus regression upon stressing stimuli, such as infectious diseases, is followed by organ reconstitution, paralleling its development in ontogeny. A narrow window of thymus development was here studied, encompassing the pro-T lymphoid precursor expansion during specification stages, by the use of...

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Bibliographic Details
Main Authors: Claudia Sondermann Freitas, Sergio Ranto Dalmau, Eliana Abdelhay
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2004-06-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
development
thymus
T-lymphocytes
Notch
growth factors
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762004000400007

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762004000400007

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