T-kininogen inhibits kinin-mediated activation of ERK in endothelial cells
Serum levels of T-kininogen increase dramatically as rats approach the end of their lifespan. Stable expression of the protein in Balb/c 3T3 fibroblasts leads to a dramatic inhibition of cell proliferation, as well as inhibition of the ERK signaling pathway. T-kininogen is a potent inhibitor of cyst...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2002-01-01
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Series: | Biological Research |
Subjects: | |
Online Access: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602002000200020 |