Alterations of milk oligosaccharides in mothers with gestational diabetes mellitus impede colonization of beneficial bacteria and development of RORγt+ Treg cell-mediated immune tolerance in neonates

Alterations of milk oligosaccharides in mothers with gestational diabetes mellitus impede colonization of beneficial bacteria and development of RORγt+ Treg cell-mediated immune tolerance in neonates

ABSTRACTGestational diabetes mellitus (GDM) is an increasing public health concern that significantly increases the risk of early childhood allergic diseases. Altered maternal milk glycobiome may strongly affect gut microbiota and enteric-specific Treg cell-mediated development of immune tolerance i...

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Bibliographic Details
Main Authors: Xinke Li, Xixi Ning, Binqi Rui, Yushuang Wang, Zengjie Lei, Da Yu, Feitong Liu, Yanjie Deng, Jieli Yuan, Wenzhe Li, Jingyu Yan, Ming Li
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Gut Microbes
Subjects:
Gestational diabetes mellitus (GDM)
human milk oligosaccharides (HMOs)
gut microbiota
RORγt+ treg cells, immune tolerance
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2023.2256749

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https://www.tandfonline.com/doi/10.1080/19490976.2023.2256749

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