Gut Prevotellaceae-GABAergic septohippocampal pathway mediates spatial memory impairment in high-fat diet-fed ovariectomized mice
Clarifying the risk factors and mechanisms that contribute to the onset of cognitive impairment following estrogen depletion is essential for improving the quality of life of older females. In the current study, using behavioral tests, 16S rDNA sequencing, in vivo and in vitro electrophysiology, opt...
Main Authors: | Shuai Zhang, Lu Zeng, Jing Ma, Wentao Xu, Yang Qu, Xuqiao Wang, Xiaobin An, Qin Wang, Yan Wu, Dongyang Wang, Haihui Chen, Jing Ai |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-02-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996123000074 |
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