Co-Grafts of Fetal Ventral Mesencephalon and Fibroblasts Expressing Sonic Hedgehog: Effect on Survival and Function of Dopamine Grafts

Fibroblasts derived from the Rat2 parental cell line were genetically modified to express the cell-associated form of Sonic hedgehog (Shh) and then co-grafted along with E14 fetal ventral mesencephalon (VM) tissue into the denervated striatum of F344 rats; fetal VM grafts alone or co-grafts using th...

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Bibliographic Details
Main Authors: David M. Yurek Ph.D., Anita Fletcher-Turner, Jennifer Moore, Ling Chai, Nagesh Mahanthappa
Format: Article
Language:English
Published: SAGE Publishing 2001-11-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/000000001783986305