SLC2A9 rs16890979 reduces uric acid absorption by kidney organoids

Introduction: The excretion and absorption of uric acid (UA) by the kidneys helps regulate serum UA levels. GLUT9, encoded by SLC2A9, is mainly expressed in the renal tubules responsible for UA absorption. SLC2A9 polymorphisms are associated with different serum UA levels. However, the lack of prope...

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Bibliographic Details
Main Authors: Shouhai Wu, Chuang Li, Yizhen Li, Junyi Liu, Cuiping Rong, Hongfei Pei, Xiong Li, Xiang Zeng, Wei Mao
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1268226/full