The relative influences of phosphometabolites and pH on action potential morphology during myocardial reperfusion: a simulation study.

Myocardial ischemia-reperfusion (IR) injury represents a constellation of pathological processes that occur when ischemic myocardium experiences a restoration of perfusion. Reentrant arrhythmias, which represent a particularly lethal manifestation of IR injury, can result when ischemic tissue exhibi...

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Bibliographic Details
Main Authors: Byron N Roberts, David J Christini
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3492384?pdf=render